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August 20, 1973

Evaluation of a General AnestheticEnflurane (Ēthrane)

JAMA. 1973;225(8):989-990. doi:10.1001/jama.1973.03220360043015

Enflurane is a nonflammable, halogenated ether, that is used as an inhalational anesthetic. Although enflurane has physical, pharmacologic, and clinical properties similar to those of halothane, it also possesses some of the clinical advantages of diethyl ether. Central nervous system excitation may be noted as anesthesia is deepened, particularly in the presence of hypocarbia. This can be terminated, without sequelae, by lightening the anesthesia.