IN THE last several years, multiple centers have identified ampicillin-resistant Haemophilus influenzae type B in septicemia, epiglottitis, meningitis, and other severe childhood infections. Such reports have prompted the recommendation to add chloramphenicol to ampicillin for the initial therapy of these infections in children. More recently, cases of childhood otitis media caused by ampicillin-resistant nontypable H influenzae have been described.1 Nontypable strains cause most cases of H influenzae otitis media but seldom cause systemic infections.6 On the other hand, H influenzae type B otitis media has been associated with meningitis or septicemia in 14% of the cases.2 This report describes a case of otitis media caused by ampicillin-resistant H influenzae type B and emphasizes the need for tympanocentesis in the diagnosis of this infection.
Report of a Case
A 2-year-old boy was seen in the Pediatric Clinic of the National Naval Medical Center in January 1975 with bilateral
Crosson FJ, Watson WC, Bailey DW, MacLowry JD. Acute Otitis Media Caused by Ampicillin-Resistant Haemophilus influenzae Type B. JAMA. 1976;236(24):2778-2779. doi:10.1001/jama.1976.03270250046027