[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 50.16.52.237. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
December 8, 1969

Preparation of Skin for Lumbar Puncture

JAMA. 1969;210(10):1923. doi:10.1001/jama.1969.03160360069024

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

To the Editor:—  Harvey Bernard, MD, (208:1196, 1969), advised preparing the skin for lumbar puncture with a hexachlorophene-containing soap followed by benzalkonium chloride. James A. Visconti, PhD, and Donald Schneider RPh; then wrote you (209:2057, 1969) pointing out, quite properly, that soaps are anionic and consequently incompatible with cationic detergents such as benzalkonium chloride. They therefore advised removing the soap by thorough rinsing with water before applying the germicide.However, it is almost impossible to remove all soap with water. Water and soap constitute a colloidal suspension; if you rub the skin after what you consider a complete removal of soap with water, you can usually stir up a few more suds, sufficient to inactivate the cationic germicide. Alcohol and soap, on the other hand, are 100% soluble in one another. If you, therefore, expect a quaternary ammonium antiseptic to act effectively after preliminary preparation with soap, 70%

×