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September 17, 1973

Lipoid Pneumonia Caused By Methenamine Mandelate Suspension

Author Affiliations

From the Department of Internal Medicine, St. Luke Hospital and the Veterans Administration Nursing Home, Ft. Thomas, Ky.

JAMA. 1973;225(12):1524-1525. doi:10.1001/jama.1973.03220400050011

Two senile individuals with dysphagia developed lipoid pneumonia subsequent to the administration of methenamine mandelate (Mandelamine) suspension, 250 mg methenamine mandelate/teaspoon. Methenamine suspension forte (double strength) contains oil of sesame (USP) and hydrogenated castor oil. Methenamine mandelate suspension contains these two ingredients plus champagne cider oil. Methenamine mandelate should be given to dysphagic patients in the form of crushed tablets mixed with semisolid food.