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Article
December 22, 1969

Primary Erythrocytosis of ChildhoodChromosome Studies Showing Marrow Polyploidy

Author Affiliations

From the Division of Hematology, Department of Medicine, Albany (NY) Medical College of Union University. (Dr. Amarose is now with the Department of Obstetrics and Gynecology, the Chicago Lying-in Hospital, the Pritzker School of Medicine, the University of Chicago.

JAMA. 1969;210(12):2274-2276. doi:10.1001/jama.1969.03160380088024
Abstract

An 8-year-old child had an increased red blood cell mass but did not have splenomegaly, leukocytosis, or thrombocytosis. This disorder is designated primary erythrocytosis of childhood. This form of benign polycythemia may have additional implications in adults. A similar polycythemic state in adult life may have its inception in childhood. Blood studies of family members were performed, and marrow chromosome studies were obtained from the patient and his father. These studies showed a high degree of polyploidy in both, and suggest further similar studies be performed in patients with this disorder.

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