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October 8, 1973

Postpartum Rubella Vaccination

Author Affiliations

Brown University Providence, RI

JAMA. 1973;226(2):200. doi:10.1001/jama.1973.03230020046026

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To the Editor.—  An important point to be considered in any postpartum rubella immunization program (225:158, 1973) is the management of the Rhnegative mother who has just given birth to an Rh-positive infant. If the woman has been sensitized she should receive anti-Rho (D) immunoglobulin after delivery. Since anti Rho (D) immunoglobulin contains a small amount of rubella antibody, anti Rho (D) and rubella vaccine should not be used simultaneously. Obviously, administration of anti Rho (D) takes precedence postpartum, and rubella immunization should be deferred.