October 15, 1973


JAMA. 1973;226(3):350-351. doi:10.1001/jama.1973.03230030062019

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The following are reasons why antibiotic usage represents an important health care problem and is worthy of study by pharmacy and therapeutics committees in the local hospitals:

  1. Adverse effects of antibiotics are frequent and may be serious. Superinfections during antibiotic therapy are of particular concern since they are one of the most important causes of fatal adverse drug reactions.

  2. Lack of control of infection is another result of the unwise use of antibiotics.

  3. Unnecessary expenditure for patient care is an important aspect of the problem, especially at a time when increased cost and complexity of health care combine with inflation to strain the nation's health care budget.

These are questions (any one of which might form the basis for study by pharmacy and therapeutics committees):

  1. What effort was made to identify the causative organism before the antibiotic was prescribed?

  2. Were sensitivity tests done on