Three patients employed as meat wrappers developed respiratory symptoms when exposed to the fumes of a polyvinyl chloride film cut with a hot wire. The patients were middle-aged women who smoked cigarettes and demonstrated reversible airway obstruction on pulmonary function testing. The cause of their symptoms is not known, but some ingredient of the polyvinyl chloride film is suspected.
Sokol WN, Aelony Y, Beall GN. Meat-Wrapper's AsthmaA New Syndrome?. JAMA. 1973;226(6):639–641. doi:10.1001/jama.1973.03230060017005