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January 19, 1970

Diseases of the Liver

Author Affiliations

Tulane University New Orleans

JAMA. 1970;211(3):503. doi:10.1001/jama.1970.03170030095027

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Descriptions of electron microscopic findings and discussions of recent developments in the surgery, biochemistry, immunology, genetics, and radiography of hepatic disease distinguish the third edition of Doctor Schiff's multiauthored book from its predecessors.

In 30 chapters, 42 authors take up almost all aspects of hepatic function and disease. After describing bilirubin metabolism, Schiff and Billing discuss clinical approaches and pitfalls to the differential diagnosis of jaundice. They emphasize utilization of historical and physical findings as well as the results of needle biopsy and other clinical laboratory examinations. Rousselot and Burchell explain techniques and indications for percutaneous splenic portography and manometry, procedures they consider invaluable for assessing anatomic and hemodynamic situations in suspected portal hypertension. And finding it determinative, practical, and safe, they employ emergency splenic pulp manometry to distinguish between a variceal or nonvariceal site of acute upper-gastrointestinal hemorrhage.

Throughout the book the authors present controversial issues, examine conflicting theories,