[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 54.146.179.146. Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Article
April 11, 1977

Paraben Allergy

Author Affiliations

From the Children's Hospital, University of Pittsburgh School of Medicine, Pittsburgh.

JAMA. 1977;237(15):1594-1595. doi:10.1001/jama.1977.03270420062018
Abstract

A hydrocortisone preparation containing methylparaben and propylparaben provoked bronchospasm and pruritis when given intravenously to an asthmatic patient, whereas another hydrocortisone preparation without paraben preservative did not. Direct and passive transfer (Prausnitz-Küstner) skin tests for immediate hypersensitivity to parabens were positive. Parabens, frequently employed as bacteriostatic agents, are capable of producing immunologically mediated, immediate systemic hypersensitivity reactions.

(JAMA 237:1594-1595, 1977)

×