March 16, 1970

General Anesthesia and the Central Nervous System: A Basic Science and Clinical Consideration

Author Affiliations

University of California Los Angeles


by Leonard C Jenkins, 544 pp, 40 illus, $17.50, Baltimore, Williams & Wilkins Co, 1969.

JAMA. 1970;211(11):1858-1859. doi:10.1001/jama.1970.03170110064028

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A close association with his own department of pharmacology has enabled Dr. Jenkins to bring together in this book much of what is presently known on neuropharmacology. A brief review of neuroanatomy is presented first, followed by a well-documented discussion of current concepts in central nervous system physiology and pharmacology. These chapters act as a prelude to the second half of the book which presents the effects of special anesthesia techniques and management of the patient with neurological disease. Thus, Dr. Jenkins develops an approach to anesthesia for neurosurgery based upon current scientific concepts.

Each chapter is intricately outlined. Reading follows easily, but frequently material beyond the basic concept of the book is included in great detail. Several subheadings can be found with a few superfluous sentences as if to fill in space. The author occasionally discusses the same subject in different chapters under related headings. The final section on