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To the Editor.—
I was most interested in the report of Takahashi and Loveland (227:762, 1974). They found a higher prevalence of bacteriuria among users of oral contraceptives at virtually all ages studied. Certain aspects of this study deserve comment. For example, the finding that the prevalence of bacteriuria did not appear to rise with age is surprising, since this is a well-described feature of urinary tract infections.My main reason for writing, however, is to provide comparative data from a study we conducted some years ago in Virginia (N Engl J Med 278:635, 1968). Data on oral contraceptive use were gathered from a control population in a study of the prevalence of bacteriuria among nuns. Our criterion for significant bacteriuria was three consecutive urine cultures containing more than 100,000 colonies per milliliter, in which the same species of bacteria was recovered in each culture. All of the patients were white
Kunin CM. Bacteriuria and Oral Contraceptives. JAMA. 1974;228(4):464. doi:10.1001/jama.1974.03230290020019