July 1, 1974

Clinical Gynecologic Endocrinology and Infertility

Author Affiliations

Rush Medical College Chicago


by Leon Speroff, Robert H. Glass, and Nathan G. Kase, 266 pp, with illus, $16.50, Williams & Wilkins Co., 1973.

JAMA. 1974;229(1):84. doi:10.1001/jama.1974.03230390060035

The objectives of this text are two-fold—first, to demonstrate that reproductive endocrinology has become a clinical science based on physiology, and second, to provide a formulation of clinical diagnosis and management founded on physiologic principles. There are four sections: physiology of female reproduction, clinical endocrinology, infertility, and clinical assays. The manner of presentation is concise and clear with the aid of excellent, bold illustrations in the form of structural formulas, charts, and graphs.

The first section is a foundation on which the second and third sections are dependent. The generally tedious presentation of normal physiology is made much more palatable by the authors' skill of presentation. The physiology of human reproduction comprises three chapters—hormonal biosynthesis, metabolism and mechanism of action, neuroendocrinology and regulation of the menstrual cycle. As the authors state, to begin a clinical book with a chapter on biochemistry only emphasizes that competent clinical judgment is founded on