August 17, 1970

Pathogenesis and Etiology of Demyelinating Diseases

Author Affiliations

University of North Carolina Chapel Hill


edited by Krystina Burdzy and P. Kallos, 701 pp, 253 illus. $34.80, Basel and New York: S. Karger AG (White Plains, NY: Albert J. Phiebig), 1969.

JAMA. 1970;213(7):1197. doi:10.1001/jama.1970.03170330077026

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This monograph is the product of an international symposium held in 1967 to explore the current ideas and research trends in multiple sclerosis. The participants were active investigators representing a variety of disciplines. Since the book is the outgrowth of a conference based upon a multidiscipline approach, it is not a unified text but a series of related papers. The editors have organized the 51 papers by the 68 participants into four broad sections: morphological aspects, virological aspects, immunological aspects, and aspects of mechanisms of other demyelinating processes caused by viruses.

Many of the papers are concerned with the role of allergic reactions and viral agents in demyelinating disorders. The individual papers range from original studies to reviews of specialized areas and are based upon basic and clinical research. Although much of the material presented had in part been previously reported, the studies included in the book were generally expanded