In a 2 1/2-year-old boy, a proptotic right lower lid developed one year after a primary abdominal mass proved to be Wilms' tumor. An orbital abscess or fungal infection was considered because the child was receiving chemotherapy. However, echography demonstrated a firm orbital mass, delineated its dimensions, and showed destruction of the orbital floor. The biopsy specimen showed metastatic tumor cells. Like neuroblastoma and certain hematologic and reticuloendothelial malignant neoplasms, Wilms' tumor may secondarily invade the ocular adnexa.
(JAMA 238:1841-1842, 1977)
Fratkin JD, Purcell JJ, Krachmer JH, Taylor JC. Wilms' Tumor Metastatic to the Orbit. JAMA. 1977;238(17):1841-1842. doi:10.1001/jama.1977.03280180045025