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September 14, 1970

Medical News

JAMA. 1970;213(11):1773-1786. doi:10.1001/jama.1970.03170370001001

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Many foreign countries now require two cholera shots  Two inoculations with cholera vaccine are "strongly recommended" by the US Center for Disease Control, Atlanta, for adults travelling to countries in Southeast Asia, the Middle East, and Northeast Africa.The recommended doses are 0.5 and 1.0 ml, given at least one week apart.A cholera pandemic is causing some countries in these areas to require the double dose. Even travelers with a valid international certificate of vaccination showing a single dose may be quarantined or placed under restrictive surveillance for up to two weeks.Physicians administering vaccine were urged to emphasize to travelers that the international certificate must be validated for both doses in order to be acceptable to quarantine authorities. Validation can be obtained at most cities, county, and state health departments.The US accepts a single dose of vaccine within six months as valid under international sanitary regulations.