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September 23, 1974

Dystonic Symptoms in ChildrenTreatment With Carbamazepine

Author Affiliations

From the departments of neurology (Drs. Geller and Christoff) and rehabilitation medicine (Dr. Kaplan), the Mount Sinai School of Medicine of the City University of New York, New York.

JAMA. 1974;229(13):1755-1757. doi:10.1001/jama.1974.03230510029017

Eight patients with dystonia, four with hereditary torsion dystonia and four with acquired dystonia, were treated with carbamazepine in doses ranging from 300 to 1,200 mg/day. Drowsiness was the only side effect and periodic blood cell counts remained normal. All have shown sustained improvement of some manifestations of their illness for periods up to one year.

(JAMA 229:1755-1757, 1974)