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November 11, 1974

Silicone Treatment of Partial Lipodystrophy

Author Affiliations

From the Institute of Reconstructive Plastic Surgery and the Department of Surgery of the New York University Medical Center, New York.

JAMA. 1974;230(6):868-870. doi:10.1001/jama.1974.03240060038029

Partial lipodystrophy, a symmetrical wasting of adipose tissue from the face and proximal part of the body, is a rare disease of undetermined etiology. Despite our ignorance of the underlying pathophysiology, the clinical manifestations are entirely reversible with liquid silicone. Percutaneous injections into the subcutaneous space of the wasted area effectively restore soft tissue contours and mask the absence of adipose tissue.

(JAMA 230:868-870, 1974)