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February 20, 1978

Medical News

JAMA. 1978;239(8):687-693. doi:10.1001/jama.1978.03280350011002

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Prolapsed mitral leaflet could be most common valve disorder  Prolapsed mitral leaflet syndrome "now appears to be the most common form of cardiac valvular disease in the United States," says a Torrance, Calif, cardiologist. He calls for a national or regional registry to pinpoint the actual incidence, complications, and warning signs of the syndrome.From 6% to 20% of otherwise healthy persons have mitral valve prolapse, says J. Michael Criley, MD, chief of cardiology at Harbor General Hospital and professor of medicine and radiological sciences at the University of California, Los Angeles, School of Medicine.For 250 years, he reminded an American Heart Association seminar, physicians have been aware of a peculiar constellation among heart sounds and murmurs. This "lub-duh-dub" extra sound has been given various names, including "systolic gallop" and "friction rub." New diagnostic techniques have become available in the last 15 years, however, and the source has