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December 2, 1974

Restless Legs SyndromeSleep-Electroencephalographic and Neurologic Findings

Author Affiliations

From the National Institute of Mental Health, Alcohol, Drug Abuse, and Mental Health Administration (Drs. Frankel and Gillin), and the National Institute of Neurological Diseases and Stroke (Dr. Patten), National Institutes of Health, Bethesda, Md. Dr. Patten is now with the Department of Neurology, Baylor College of Medicine, Houston.

JAMA. 1974;230(9):1302-1303. doi:10.1001/jama.1974.03240090042025

The unusual sensory and motor symptoms of the restless legs syndrome are described in general and as experienced by a 48-year-old woman with severe insomnia secondary to these symptoms. The neurologic evaluation of this patient showed definite evidence of motor neuron disease as reflected in abnormalities in the electromyogram, muscle biopsy specimen, and cerebrospinal fluid.

(JAMA 230:1302-1303, 1974)