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February 27, 1978

Systemic Mastocytosis and Pulmonary Eosinophilic Granuloma

Author Affiliations

From the Department of Dermatology, National Naval Medical Center, Bethesda, Md.

JAMA. 1978;239(9):856-857. doi:10.1001/jama.1978.03280360052020

DURING the clinical examination of a patient with urticaria pigmentosa for systemic mast cell disease, findings of a chest roentgenogram were abnormal. This condition was subsequently diagnosed to be eosinophilic granuloma. The patient had systemic mastocytosis and eosinophilic granuloma of the lung, a combination that to our knowledge has not been previously reported.

Report of a Case  A 22-year-old woman was initially examined in the Dermatology Clinic at the National Naval Medical Center in Bethesda, Md, on July 25, 1974. The main complaint was of pruritic lesions on her chest and abdomen. These lesions were first noted at the age of 17 years and have increased in number. The patient also complained of headaches, dizziness, nausea, diarrhea, anorexia, and dyspnea. These symptoms frequently occurred during a hot shower or shortly after the ingestion of alcoholic beverages or aspirin. The lesions would also urticate with these stimuli. There was no history