December 16, 1974

Immunological Aspects of Transplantation Surgery

Author Affiliations

Northwestern University Medical School Chicago


edited by Roy Calne, 342 pp, with illus, $19.75, New York, John Wiley, 1974.

JAMA. 1974;230(11):1586-1587. doi:10.1001/jama.1974.03240110072032

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This slim but expensive volume reflects the quantum of change that has occurred in the 15 years since the appearance of Sir Michael Woodruff's tome, Transplantation of Tissues and Organs. In 1960, when that book was published, there was concern with the immunologic aspects of transplantation, but this was not yet a dominant theme. There was as much concern with moving tissues around in the body, which was also called transplantation, as with actual allografting and xenografting of living parts. Indeed, terminology itself has changed in that interim, so that terms such as homografting and heterografting are seldom used now. The very fact that surgeons can write intelligently and, at times, brilliantly about the immunologic manipulations attending organ grafting is another index of the degree of change that has occurred in this surgical art.

Although this book was edited in England, it contains major contributions from this side of the