† A second case of severe limb malformations was observed following maternal use of haloperidol early in the first trimester of pregnancy. Haloperidol is teratogenic in mice, and may be teratogenic in humans.
(JAMA 231:62-64, 1975)
Kopelman AE, McCullar FW, Heggeness L. Limb Malformations Following Maternal Use of Haloperidol. JAMA. 1975;231(1):62-64. doi:10.1001/jama.1975.03240130044026