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January 6, 1975

Limb Malformations Following Maternal Use of Haloperidol

Author Affiliations

From the Department of Pediatrics, University of Rochester School of Medicine, Rochester General Hospital (Drs. Kopelman and McCullar), and the Department of Pathology, Rochester General Hospital (Dr. Heggeness), Rochester, NY.

JAMA. 1975;231(1):62-64. doi:10.1001/jama.1975.03240130044026

† A second case of severe limb malformations was observed following maternal use of haloperidol early in the first trimester of pregnancy. Haloperidol is teratogenic in mice, and may be teratogenic in humans.

(JAMA 231:62-64, 1975)