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January 13, 1975

Osteoblastic Repair of Osteolytic Tumor Metastases Following Treatment

Author Affiliations

Montefiore Hospital New York

JAMA. 1975;231(2):135. doi:10.1001/jama.1975.03240140009006

To the Editor.—  Osteoblastic repair of osteolytic bone lesions has been reported as a slow process taking many months.1,2 In the present case, improvement in roentgenographic examination in six weeks was accompanied by sufficient clinical improvement to permit her leaving the wheelchair and performing house-hold duties.

Report of a Case.—  This 30-year-old woman was first seen in October 1969, one month after having her fourth child. She complained of shortness of breath and back pain. Significant history included surgery for a benign breast cyst in 1966. However, in May 1969, a left radical mastectomy was done, permitting the patient to carry to term thereafter.In October, the salient findings included a gibbus with tenderness of the first lumbar vertebra, multiple skin nodules along the left lateral chest wall, and bilateral pleural effusions. Roentgenographic examination showed the expected collapse of the first lumbar vertebra and additional osteolytic bone lesions in