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February 17, 1975

Controlled Study of the Cytotoxic Food Test

Author Affiliations

From the sections of allergy-immunology of the departments of medicine (Drs. Lieberman and Bjelland and Ms. Rice) and pediatrics (Dr. Crawford), University of Tennessee College of Medicine, Memphis. Dr. Connell is Student Research Fellow of the Allergy Foundation of America.

JAMA. 1975;231(7):728-730. doi:10.1001/jama.1975.03240190032012

The cytotoxic food test was not found to be an accurate method for diagnosing atopic reactions to foods. Claims that the test correlated with other untoward reactions to foods (eg, headache, diarrhea, fatigue) could not be corroborated. The test itself is time-consuming, dependent on subjective interpretation, and inconsistent in results when repetitive runs are performed on the same patient.

(JAMA 231:728-730, 1975)