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To the Editor.—
The question is asked in The Journal (229:1661, 1974): "Why are the coronary arteries so prone to thrombosis?" It seems worthwhile to consider first: "Are the coronary arteries unusually prone to thrombosis?"Coronary artery thrombosis and cerebral artery thrombosis both result in a frightening illness, readily diagnosed, commonly resulting in death, and therefore often seen at necropsy. Are the cerebral arteries also prone to thrombosis?Renal and splenic arteries commonly show severe atheroma, and infarcts or scars are common chance findings in the kidney and spleen at necropsy. Thrombosis is an occasional unexpected finding in small arteries in other regions. Unless the vascular disease is widespread or severe, the resultant condition is usually minor or reversible.Thus: "Is thrombosis unusually common in the coronary arteries, or is it just commonly diagnosed?"
Warren JR. Coronary Artery Thrombosis. JAMA. 1975;231(11):1135. doi:10.1001/jama.1975.03240230011008