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March 17, 1975

Operative Morbidity and Mortality in Renovascular Disease

Author Affiliations

From the Department of Medicine (Drs. Franklin and Maxwell), University of California at Los Angeles; Nephrology and Hypertension Service (Dr. Franklin and Mr. Varady), Mt. Sinai Division, Cedars-Sinai Medical Center, Los Angeles (Dr. Maxwell); Division of Urology, University of Maryland, Baltimore (Dr. Young); Vanderbilt University School of Medicine, Nashville, Tenn (Dr. Foster); Stanford University, Palo Alto, Calif (Dr. Palmer); Department of Surgery, Urology Section, University of Michigan, Ann Arbor (Dr. Cerny); and the Henry Ford Hospital, Detroit (Dr. Cerny). Dr. Palmer is now at the University of California, Department of Urology, Davis.

JAMA. 1975;231(11):1148-1153. doi:10.1001/jama.1975.03240230022013

There were 104 major complications (13.1%) and 34 deaths (5.9%) among 502 patients with evidence of renovascular, disease who underwent 577 operative procedures. The operative mortality rate in patients with atherosclerotic renovascular disease was 9.3% vs 3.4% with fibromuscular hyperplasia.

Important determinants of renovascular operative mortality are (1) cause of disease, (2) presence of coronary artery disease, (3) presence of bilateral renal functional impairment, (4) the complexity of the renal operative procedure, and (5) concurrent extrarenal surgery.

(JAMA 231:1148-1153, 1975)