[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
July 14, 1978

Cardiac Complications of Protein-Sparing Modified Fasting

Author Affiliations

From the Departments of Medicine (Drs Brown and Spicer) and Pathology (Drs Yetter and Jones), William Beaumont Army Medical Center, El Paso, Tex.

JAMA. 1978;240(2):120-122. doi:10.1001/jama.1978.03290020042020

Cardiovascular abnormalities developed in a patient during a proteinsparing modified fasting diet. Syncope was the complaint at the time of examination. Hypotension, persistent QTc interval prolongation, and a low QRS voltage were observed before the development of refractory ventricular tachycardia. At autopsy, antemortem thrombi were attached to the left ventricular endocardium and a fenestrated aortic valvule. Strick proteinsparing modified fasting is not without risk of sudden death even with close medical supervision.

(JAMA 240:120-122, 1978)