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July 28, 1978

Gilles de la Tourette Syndrome

Author Affiliations

Bowman Gray School of Medicine Winston-Salem, NC

JAMA. 1978;240(4):394. doi:10.1001/jama.1978.03290040072036

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Gilles de la Tourette in 1885 described nine patients with multiple tics. Tourette characterized the condition as the onset of multiple tics in childhood with a fluctuating chronic course associated with verbal tics and echolalia. Coprolalia occurred in about half of his patients. Tourette noticed that his patients did not deteriorate psychologically and that they were able to maintain their sanity despite their affliction. Charcot named the disease after Tourette. Wilson, who translated the classical text of Miege and Fiendel on tics, wrote that he could find no case report of recent times.

The authors of this book state that they have collected detailed data on more than 400 patients with Gilles de la Tourette's syndrome. Their data include genetic, demographic, medical, neurological, developmental, psychological, and social information along with detailed histories of the symptoms and the courses of the patients with and without treatment. Shapiro and his colleagues note