by Stephen K. Carter, Marie T. Bakowski, and Kurt Hellman, ed 2; 379 pp, with illus, paper, $18.50, New York, John Wiley & Sons Inc, 1981.
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"The critical factor... is not to make it so complex that it cannot be routinely used by the oncologic community." Although this statement by the authors is intended to delimit a system of classifying cancer, their book appears to have been produced with this concept in mind.
Chemotherapy of Cancer is a concise, authoritative review of the principles and practices of cancer chemotherapy. The introductory material lucidly explains the theoretical and practical considerations underlying any regimen for the management of the patient with cancer. Such basic concepts as tumor cell biology and pharmacokinetics are explained simply, leading to a discussion of factors affecting the choice of chemotherapy. In the next section, all of the widely used agents are described individually in outline form under headings such as "Synonyms," "Administration," "Dosage," "Mechanism of Action," "Cell-Cycle Specificity," "Pharmacokinetics," "Toxicity," and "Major Indications for Use." This is pertinent information for the practitioner who
Polk IJ. Chemotherapy of Cancer. JAMA. 1981;246(9):1026-1027. doi:10.1001/jama.1981.03320090072041