Women with anorexia nervosa have reduced skeletal mass. Both anorexia and osteopenia are less common in men. We describe a 22-year-old man with anorexia nervosa and severe osteopenia involving both cortical and trabecular bone who developed a pelvic fracture and multiple vertebral compression fractures. He was found to have secondary hypogonadotropic hypogonadism that was reversible with weight gain. This case illustrates the need to consider osteopenia as a potential complication of anorexia nervosa in males as well as females.
Rigotti NA, Neer RM, Jameson L. Osteopenia and Bone Fractures in a Man With Anorexia Nervosa and Hypogonadism. JAMA. 1986;256(3):385-388. doi:10.1001/jama.1986.03380030087034