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July 18, 1986

Mycobacterium tuberculosis Bacteremia in the Acquired Immunodeficiency Syndrome

Author Affiliations

From the Division of Infectious Diseases, Department of Medicine (Drs Saltzman, Friedland, and Klein), and Division of Microbiology, Department of Pathology (Drs Motyl and McKitrick), Montefiore Medical Center; and Departments of Medicine (Drs Saltzman, Friedland, and Klein) and Pathology (Drs Motyl and McKitrick), Albert Einstein College of Medicine, Bronx, NY.

JAMA. 1986;256(3):390-391. doi:10.1001/jama.1986.03380030092036

THE ACQUIRED immunodeficiency syndrome (AIDS) is characterized by a defect in cellular immunity and the occurrence of opportunistic infections or unusual malignant neoplasms. The most commonly reported bacterial infection suggestive of a defect in cellular immunity, which meets the Centers for Disease Control (Atlanta) case definition for AIDS, is disseminated Mycobacterium avium-intracellulare infection.1 Disseminated infection due to Mycobacterium tuberculosis has also been reported in AIDS.2 Bacteremia is common in disseminated M avium-intracellulare infection in patients with AIDS.3 In contrast, bacteremia in disseminated M tuberculosis is rare4-6 and has not been reported previously in patients with AIDS, to our knowledge. We recently diagnosed disseminated infection due to M tuberculosis, in which bacteremia also occurred, in an intravenous drug abuser with AIDS.

Report of a Case  A 35-year-old man with a three- to five-year history of intravenous heroin and cocaine abuse developed anorexia and weight loss in November