September 18, 1981

Management of Acute Hyperparathyroidism in a Community Hospital

Author Affiliations

From the Departments of Medicine and Surgery, St Luke's Hospital, San Francisco (Dr Bohannan), and John Muir Hospital, Walnut Creek, Calif (Drs Reitz and Hauer). Dr Wang, Department of Endocrine Surgery, Massachusetts General Hospital, and Department of Surgery, Harvard Medical School, Boston, is visiting professor of surgery, St Luke's and John Muir Hospitals.

JAMA. 1981;246(12):1334-1336. doi:10.1001/jama.1981.03320120038024

Primary hyperparathyroidism is a common entity that routinely lends itself to prompt surgical cure. Infrequently, multiple surgical explorations are required to effect a cure. A case is reported of a 27-year-old man with hypercalcemia and nephrocalcinosis. The initial surgical exploration failed to identify the abnormal parathyroid tissue. Hypercalcemia necessitated rigorous antihypercalcemic therapy; three subsequent operations, including a mediastinal exploration, were unsuccessful. On the fifth exploration, which took barely an hour, a 35-g adenoma was removed from the left superior posterior mediastinum. This report illustrates that a detailed knowledge of the possible locations of aberrant parathyroid tissue and the skills of the operating surgeon are the sine qua non for those patients requiring one or more parathyroid reexplorations.

(JAMA 1981;246:1334-1336)