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November 17, 1978

Pathobiology: How Disease Happens

Author Affiliations

William Beaumont Hospital Royal Oak, Mich

JAMA. 1978;240(21):2331-2332. doi:10.1001/jama.1978.03290210113047

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Students and teachers alike will find this new book a refreshing text that fills a void in instructional material for allied health care students. Pathobiology summarizes the entire spectrum of health and disease in ten concise chapters.

It is written in a style that conveys vitality and clarity for the student who is not interested in learning "more than he wanted to know" about pathology. All major disease categories are considered in some depth except trauma and poisoning. The chapters on genetics, cell biology, immunology, and neoplasia are outstanding.

The author sets the stage for the description of disease mechanisms by first reviewing the normal dynamics of cells and tissues in health. Twenty-one brief case histories, inserted throughout the text, illustrate the clinical sequelae of underlying disease processes. These case histories emphasize pathologic mechanisms and their clinical relevance.

Suggested additional readings at the end of each chapter are carefully selected,