To the Editor.
—Because no recognized guidelines specifically address prophylactic treatments such as zidovudine and primary Pneumocystis carinii pneumonia prophylaxis for pregnant women infected with the human immunodeficiency virus (HIV),1,2 current physician prescribing practices for such women may vary widely. In this analysis, we reviewed medical records of a sample of pregnant women from the Adult and Adolescent Spectrum of HIV Disease Project (ASD), a large, multisite, observational study started in January 1990 in which medical records of HIV-infected persons receiving medical care are reviewed at regular intervals.3 Among2050 women identified before November 1992, 367 (18%) had been pregnant during the previous year. Using information collected routinely in this project and additional information specifically abstracted for the pregnant women in this analysis (eg, exact dates of pregnancy and drug prescription), we examined physicians' prescription practices for 86 pregnant women with CD4+ T-lymphocyte cell counts less than 0.50×109
Wortley P, Chu SY, Blostein J, Farley T, Morrison L, Kovacs A, Thompson S. Care of Pregnant Women Infected With HIV. JAMA. 1994;271(4):271. doi:10.1001/jama.1994.03510280033020