January 26, 1994

Care of Pregnant Women Infected With HIV-Reply

Author Affiliations

State University of New York Health Science Center at Brooklyn

JAMA. 1994;271(4):272. doi:10.1001/jama.1994.03510280033021

In Reply.  —The social consequences of HIV infection can be as devastating as the medical consequences. That is quite often the case for women, whose access to treatment and research frequently has been circumscribed by gender or childbearing capacity. Participation in fetal HIV research, for example, still requires paternal consent even if maternal benefit could also derive from such participation.1 In addition, for some years Public Health Service documents recommended that consideration of P carinii pneumonia prophylaxis with pentamidine be deferred until after pregnancy.2 Although more recent documents do not mention that exclusion, neither do they specifically recommend treating pregnant women. The failure of several (7/16) women in the ASD project to receive needed prophylaxis suggests that the absence of proscription does not equal prescription and reinforces the authors' plea for HIV treatment guidelines to address treatment during pregnancy.Although the treatment given to these women was not

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