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Article
January 26, 1994

What Is Necessary for Proof? Is 95% Sure Unrealistic?

Author Affiliations

University of Florida Health Science Center Jacksonville

JAMA. 1994;271(4):272. doi:10.1001/jama.1994.03510280034022
Abstract

To the Editor.  —The discussion by Dr Eddy1 of what is needed for evidence to be "sufficient" when evaluating medical treatments deserves further exploration. Even if we can agree on appropriate end points, study designs, and use of expert knowledge, the question of how certain we must be that treatment A is beneficial compared with treatment B is still

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