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February 23, 1979

Postcholecystectomy Diarrhea

Author Affiliations

From the Department of Medicine, The Johns Hopkins Hospital (Drs Hutcheon, Bayless, and Gadacz), and the Loch Raven Veterans Administration Hospital (Dr Gadacz), Baltimore.

JAMA. 1979;241(8):823-824. doi:10.1001/jama.1979.03290340041024

Diarrhea developed in three patients following cholecystectomy. Fecal bile-acid excretion was elevated in the two patients for whom it was measured. All three patients' diarrhea resolved with cholestyramine resin therapy. This experience suggests that gallbladder removal may lead to a bile-acid-mediated diarrhea in some patients, and that this condition appears to respond to cholestyramine therapy.

(JAMA 241:823-824, 1979)