[Skip to Content]
[Skip to Content Landing]
Article
April 17, 1987

Medical News & Perspectives

JAMA. 1987;257(15):1999-2007. doi:10.1001/jama.1987.03390150013003

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.

Abstract

Routine Screening Considered to End Perinatal Hepatitis Transmission  THE CENTERS for Disease Control (CDC) is giving serious consideration to broadening the present recommendations for screening pregnant women for hepatitis B surface antigen (HBsAg). There is now overwhelming evidence that, by identifying mothers who are carriers of hepatitis B virus and acting on that information, transmission of the virus can be interrupted.When a mother is identified as positive for the virus, her newborn infant can receive high-titer immune globulin and immunization with hepatitis B vaccine. Studies have shown that in well over 90% of cases this will prevent the infant from acquiring the virus with its attendant risk of developing chronic liver disease.When women are both HBsAg and e antigen positive, there is an 80% to 90% risk of their infants becoming infected with the virus and becoming chronic carriers. The e antigen is a hepatitis B marker

×