Ignorance of phototoxicity by the general biomedical community constitutes a health hazard. Certain food colorants and dyes proposed for use in angiography produce lethal effects in cells and whole organisms on light exposure but not in the dark. Yet light-relatedness is usually neglected in toxicity studies. We urge that the specific involvement of light be considered whenever the toxicity of a light-absorbing substance is assessed.
(JAMA 242:453-454, 1979)
Valenzeno DP, Pooler JP. PhototoxicityThe Neglected Factor. JAMA. 1979;242(5):453-454. doi:10.1001/jama.1979.03300050043026