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March 9, 1994

From the National Institutes of Health

Author Affiliations

Director National Heart, Lung, and Blood Institute

JAMA. 1994;271(10):738. doi:10.1001/jama.1994.03510340024010

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Speed Urged for Thrombolytic Therapy in Acute Myocardial Infarction  : Treatment of all eligible patients with acute myocardial infarction (AMI) with thrombolytic drugs within 30 minutes of arrival at a hospital should be a goal for all emergency departments, according to the first published recommendations (Ann Emerg Med. 1994;23:311-329) of the National Heart Attack Alert Program (NHAAP) Coordinating Committee. The National Heart, Lung, and Blood Institute (NHLBI) established the committee, which includes representatives from 39 scientific, professional, governmental, and voluntary organizations, to assist the NHAAP in achieving its goal of reducing AMI morbidity and mortality, including AMI-related sudden death. The new report—prepared by an NHAAP working group cochaired by Costas Lambrew, MD, Maine Medical Center, Portland, and Mark Smith, MD, George Washington University Medical Center, Washington, DC—lays out the scientific rationale for this recommendation and proposes specific measures emergency departments should take to minimize time to reperfusion and thus maximize myocardial

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