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September 28, 1979

Mucormycosis in a Renal Transplant Recipient With Successful Outcome

Author Affiliations

From the Kraftsow Renal Section and Women's League for Medical Research Laboratories (Drs Henriquez, Raja, Kramer, and Rosenbaum) and the Section of Infectious Diseases, Department of Medicine (Dr Levy), Albert Einstein Medical Center, Philadelphia.

JAMA. 1979;242(13):1397-1399. doi:10.1001/jama.1979.03300130041018

MUCORMYCOSIS is usually a fatal disease that occurs in patients with uncontrolled diabetes mellitus, in patients with an abnormal immunologic system such as immunodeficiency states, or in patients receiving immunosuppressive drugs.1 Few cases of mucormycosis have been reported in patients with renal transplants. With the increasing number of renal transplants in diabetics, mucormycosis may be seen in these patients. It is important to be aware of the clinical manifestations, diagnosis, and treatment of this fungal disease.

A patient with juvenile-onset diabetes mellitus experienced mucormycosis with invasion of sinuses and hard palate two years after kidney transplantation. The patient responded to treatment with amphotericin B, surgical debridement of sinuses, and discontinuation of therapy with immunosuppressive drugs.

Report of a Case  A 20-year-old woman was admitted to the Albert Einstein Medical Center in October 1977 with the chief complaint of left frontal headache, malaise, and numbness in the left side of