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October 26, 1979

Use of Timolol

Author Affiliations

Wills Eye Hospital Thomas Jefferson University Philadelphia

JAMA. 1979;242(17):1849. doi:10.1001/jama.1979.03300170015013

To the Editor.—  The Journal is to be congratulated for publication of the article on timolol maleate (241:2301, 1979). At the Wills Eye Hospital, we have had considerable experience in the investigational and clinical use of timolol. We believe a few comments should be added to Dr Kosman's review.Timolol is effective in lowering intraocular pressure in patients with a variety of types of glaucoma, as well as in patients with primary open angle glaucoma.1 Its use, then, need not be limited to patients with primary open angle glaucoma.In a significant number of patients, the intraocular pressure-lowering effect of timolol is greater immediately after instituting use of the medication.2 Valid conclusion regarding the long-term effect on intraocular pressure is best deferred until the patient has been receiving the medication approximately one month. When considering the effect of timolol in such a time frame, it will be noted