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November 9, 1979

Digoxin Overdose Limitations of Hemoperfusion-Hemodialysis Treatment

Author Affiliations

From the Division of Nephrology, Department of Medicine, University of California Medical Center, San Diego.

JAMA. 1979;242(19):2100-2101. doi:10.1001/jama.1979.03300190040024

We used charcoal hemoperfusion coupled with hemodialysis to treat a woman with massive digoxin ingestion complicated by hyperkalemia. Although dialysis controlled the serum potassium levels, hemoperfusion removed less than 1% of the total ingested dose. Hemoperfusion has a relatively minor impact on digoxin elimination and remains of unproved value in the therapy for digoxin overdose.

(JAMA 242:2100-2101, 1979)