Best known as a writer of detective fiction, Arthur Conan Doyle was formally trained as a physician and practiced medicine from 1881 to 1891. He wrote articles on several medical subjects as well as an extensive thesis on tabes dorsalis for an MD degree. The thesis is a comprehensive and well-written summation of the subject. Its literary qualities were as unique to scientific writing in his day as they would be today.
Rodin AE, Key JD. Arthur Conan Doyle's Thesis on Tabes Dorsalis. JAMA. 1982;247(5):646-650. doi:10.1001/jama.1982.03320300050022