Analgesia with a mixture containing 50% nitrous oxide and 50% oxygen (Nitronox) was evaluated in 47 patients with abdominal pain, chest pain, musculoskeletal trauma, and burns. Of these, 93.6% experienced either partial or complete relief of pain. There were no complications attributed to its application; the short duration of action makes its use suitable during emergency transportation.
(JAMA 242:2418-2419, 1979)
Thal ER, Montgomery SJ, Atkins JM, Roberts BG. Self-administered Analgesia With Nitrous OxideAdjunctive Aid for Emergency Medical Care Systems. JAMA. 1979;242(22):2418-2419. doi:10.1001/jama.1979.03300220030018