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Article
September 11, 1987

Kartagener's Syndrome With Normal Spermatozoa

Author Affiliations

Tiruvella Medical Mission India

Tiruvella Medical Mission India

JAMA. 1987;258(10):1329-1330. doi:10.1001/jama.1987.03400100063014
Abstract

To the Editor.—  Kartagener's syndrome (chronic sinopulmonary symptoms and situs inversus) was shown to be a part of the immotile-cilia syndrome (chronic sinopulmonary symptoms and male sterility) when Afzelius and coworkers demonstrated that males with the immotile-cilia syndrome had immotile (or dysmotile) respiratory cilia and spermatozoa and that 50% of cases of the immotile-cilia syndrome had situs inversus.1,2 The immotility is attributed to an ultrastructural defect of the respiratory cilium and sperm tail.1 The inheritance is autosomal recessive. Absence of frontal sinuses is a recognized association.2This is to my knowledge the second report of a case of Kartagener's syndrome with normal spermatozoa. The patient had chronic sinopulmonary symptoms, situs inversus, and absent frontal sinuses, while his spermatozoa had normal motility, ultrastructure, and fertilizing capacity. Thus, the entity can be regarded as a new subgroup of the immotile-cilia syndrome.

Report of a Case.—  A bachelor, aged 26

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