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We appreciate the comments of Drs Georgitis and Hofeldt. In response to their question, the time relationships were as follows: At 7 PM, the pH was 7.33; Pco2, 48 mm Hg; Po2, 51 mm Hg. At 7:10 PM oxygen therapy was begun. At 8 PM, pH was 7.31; Pco2, 46 mm Hg; Po2, 72 mm Hg. At 11:45 PM the patient was alert and responsive. At 2 AM the patient was lethargic, and levothyroxine was administered intravenously (IV). At 2:10 AM, after cardiopulmonary resuscitation, pH was 7.34; Pco2, 42 mm Hg; Po2, 58 mm Hg.The Pco2, was measured at 37 °C and not corrected for the patient's temperature. With the appropriate correction for hypothermia, the Pco2 at 8 PM after one hour on oxygen becomes 41.3 mm Hg.Thus, it does not appear that in this instance oxygen therapy
Bacci V, Schussler GC, Bhogal RS, Carter AC. Myxedema Coma and Cardiac Arrest-Reply. JAMA. 1982;247(7):980. doi:10.1001/jama.1982.03320320020021