February 19, 1982

Clinical Use of Drugs in Patients With Kidney and Liver Disease

Author Affiliations

Veterans Administration Medical Center University of Oklahoma College of Medicine Oklahoma City


edited by Robert J. Anderson and Robert W. Schrier (Drug Reference Tables, edited by John G. Gambertoglio), 348 pp, 144 illus, $32.50, Philadelphia, WB Saunders Co, 1981.

JAMA. 1982;247(7):1050-1051. doi:10.1001/jama.1982.03320320074043

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The 20-chapter Clinical Use of Drugs in Patients With Kidney and Liver Disease is a first-of-a-kind book sorely needed by practicing physicians of all disciplines. Over the last two decades there has been increasing use in renal disease of drugs such as corticosteroids and immunosuppressives and, in hypertension, vasodilators or blocking agents. Diuretics also are commonly used in renal disease, hypertension, and liver disease. These drugs are potent and effective, but are often associated with side effects. Side effects can be mild, requiring reduction of the dosage, or alarming, warranting complete withdrawal. Prompt and early recognition of side effects, especially in patients with renal insufficiency, is vitally important to avert irreversible adverse effects. Monitoring of dosage and side effects and methods to control toxicity are discussed with remarkable explicitness.

The book is extremely well written, up to date, and easily read, with comprehensive references to articles on drug usage. The