Calcitriol was used successfully to treat a patient with hypoparathyroidism during pregnancy. Increasing dosages of calcitriol were needed during the last trimester with a prompt decrease in the requirement after delivery. The dosage changes appear to mirror the pattern of endogenous synthesis of calcitriol in normal pregnant women.
(JAMA 243:254-255, 1980)
Sadeghi-Nejad A, Wolfsdorf JI, Senior B. Hypoparathyroidism and Pregnancy Treatment With Calcitriol. JAMA. 1980;243(3):254-255. doi:10.1001/jama.1980.03300290036018